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PT-141

CAS #: 189691-06-3

PT-141

Research Use Only

All products are intended solely for laboratory research and are not for human or animal consumption. By purchasing, the buyer agrees to use these products in compliance with all applicable laws.

PT-141 Overview

PT-141, also known as Bremelanotide, is a synthetic peptide analog of α-melanocyte-stimulating hormone (α-MSH). It is studied in laboratory and preclinical models for its ability to activate melanocortin receptors (MC3R and MC4R), which are involved in neuroendocrine signaling, energy regulation, and vascular pathways.

Dorr R.T. et al. (1996).

History

PT-141 was developed through research into melanocortin-class peptides, originally derived from modifications of Melanotan II. While Melanotan II was primarily studied for its pigmentation pathway properties, PT-141 was synthesized to focus on central target receptor activity. Since its discovery, PT-141 has been investigated in models of neuroendocrine function, vascular signaling, and peptide-receptor dynamics.

Shadiack A.M. et al. (2002).

PT-141 Structure

CAS #: 189691-06-3

Molecular Formula: C₅₀H₆₈N₁₄O₁₀

Molecular Weight: 1025.2 g/mol

PubChem ID: 6918280

Research Findings

PT-141 has been studied in neurological, endocrine, and systemic models, with research highlighting its activity in target receptor pathways, neuroendocrine signaling, and systemic dynamics. Studies also report effects on central nervous system activity, endocrine modulation, and vascular responses in preclinical settings.

Key Areas of Research:

  • Neurological: CNS activity, signaling, pathways

  • Endocrine: Modulation, signaling dynamics

  • Systemic: Vascular responses, viability, resilience

Together, these findings suggest experimental potential for PT-141 across neurological, endocrine, and systemic pathways. By engaging target receptor pathways and influencing neuroendocrine activity, PT-141 provides a versatile platform for research into signaling biology, systemic dynamics, and central pathway characterization in laboratory settings.

Shadiack A.M. et al., 2004

Our Process

STEP 1

Precision Lyophilization

Manufactured in a controlled U.S. facility under strict compounding standards.

STEP 2

Verified Purity

Every batch third-party tested with HPLC and mass spectrometry.

STEP 3

Same-Day Fulfillment

Orders dispatched same-day from our U.S. facility.
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Frequently Asked Questions

Orders dispatched same-day from our U.S. facility.

Each vial contains exactly what’s shown on the label. For example, a 10mg vial has exactly 10mg of lyophilized peptide. Researchers can divide it into smaller portions—like four 2.5mg measurements—but the total amount remains 10mg.

Peptides are supplied as lyophilized powder. They do not come reconstituted, and any extra supplies must be sourced separately for research applications.
In lyophilized powder form, peptides stay stable for up to 2 years. After reconstitution, it should be refrigerated and is generally stable for up to 2 months.

Products from Raw Peptides do not include usage instructions, as they are strictly for in vitro research and prohibited by law for human or animal use. Misuse or unlawful application will result in permanent denial of service.

Lyophilized peptides should be stored away from heat and light. Once reconstituted, they must be refrigerated to maintain stability and efficacy.